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Verma, Vikas Kumar
- A Review on Diabetes and Its Management
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1 Saroj Institute of Technology and Management, Ahimamau P.O. Arjunganj Sultanpur Road, Lucknow- 226002,Uttar Pradesh, IN
1 Saroj Institute of Technology and Management, Ahimamau P.O. Arjunganj Sultanpur Road, Lucknow- 226002,Uttar Pradesh, IN
Source
Asian Journal of Pharmaceutical Research, Vol 3, No 1 (2013), Pagination: 28-33Abstract
The current approach to the treatment of both type 1 and type 2 diabetes is to achieve the best possible glucose control. Past clinical trials have shown that glycemia plays a key role in the prevention of both macro- and microvascular complications. During the past 20 years, a number of new medications to control blood glucose have been introduced, and new approaches to the use of older medications have been developed. Weight and diabetes, especially type 2 diabetes, are closely related. Obesity is a major risk factor for the development of type 2 diabetes, and the current increase in obesity in our society has fueled a major increase in the expression of this disease. Not only does weight, through the mechanism of insulin resistance, aggravate hyperglycemia, it also increases the risk for hypertension, hyperlipidemia, and other conditions that lead to cardiovascular disease.Keywords
Glycemia, Obesity, Hyperglycemia, Hypertension, Hyperlipidemia
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- Beating Cancer with Natural Plant Sources
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1 Saroj Institute of Technology & Management, Ahimamau , P.O. Arjunganj , Sultanpur Road, Lucknow-226002, Uttar Pradesh, IN
1 Saroj Institute of Technology & Management, Ahimamau , P.O. Arjunganj , Sultanpur Road, Lucknow-226002, Uttar Pradesh, IN
Source
Asian Journal of Pharmacy and Technology, Vol 3, No 2 (2013), Pagination: 39-44Abstract
Medicinal plants continue to play a central role in the healthcare system of large proportions of the world's population. This is particularly true in developing countries, where herbal medicine has a long and uninterrupted history of use. Continuous usage of herbal medicine by a large proportion of the population in the developing countries is largely due to the high cost of Western pharmaceuticals and healthcare. Every year, millions of people are diagnosed with cancer, leading to death in a majority of the cases. Specific part of it is formulated into suitable preparations compressed as tablets or made into pills, used to make infusions, extracts, tinctures, etc., or mixed with excipients to make lotions, ointments, creams, etc. Few herbal drugs are subject to legislative control. The plant based drug discovery resulted mainly in the development of anticancer agents including plants (vincristine, vinblastine, etoposide, paclitaxel, camptothecin, topotecan and irinotecan). Beside this there is numerous agents identified from fruits and vegetables can used in anticancer therapy. The agents include curcumin (turmeric), resveratrol (red grapes, peanuts and berries), genistein (soybean), diallyl sulfide, S-allyl cysteine (allium), allicin (garlic), lycopene (tomato), capsaicin (red chilli), diosgenin, 6-gingerol (ginger), ellagic acid (pomegranate), ursolic acid (apple, pears), silymarin (milk thistle), anethol, catechins, eugenol, indole-3-carbinol, limonene, beta carotene, and dietary fiber. In this review active principle derived from natural products are offering a great opportunity to evaluate not only totally new chemical classes of anticancer agents, but also novel lead compound and potentially relevant mechanisms of action.Keywords
Herbal Medicine, Pharmaceuticals, Healthcare, Infusions, Extracts, Tinctures, Anticancer AgentsReferences
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- Ancuceanu, R.V., Istudor, V., (2004). Pharmacologically active natural compounds for lung cancer. Altern Med Rev.,9: 402-419.
- Deng, F., Lu, J.J., Liu, H.Y., Lin, L.P., Ding, J., Zhang, J.S., (2011). Synthesis and antitumor activity of novel salvicine analogues. Chin Chem Lett.,22: 25-28.
- Dixon, R.A., Ferreira, D., (2002). Molecules of interest: genistein. Phytochemistry.,60: 205-211.
- Kingston, D.G.I., (2007). The shape of things to come: structural and synthetic studies of taxol and related compounds. Phytochemistry.,68(14): 1844-1854.
- Okouneva, T., Hill, B.T., Wilson, L., Jordan, M.A., (2003). The effects of vinflunine, vinorelbine, and vinblastine on centromere dynamics. Mol Cancer Ther.,2: 427-436
- Cymbopogon Citrates Oil Showing Antimicrobial Activity against Microbes of Environmental, Clinical and Food Origin
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Authors
Affiliations
1 Saroj Institute of Technology & Management, Ahimamau P.O. Arjunganj Sultanpur Road, Lucknow-226002,Uttar Pradesh
2 Saroj Institute of Technology & Management, Ahimamau P.O. Arjunganj Sultanpur Road, Lucknow-226002,Uttar Pradesh, IN
1 Saroj Institute of Technology & Management, Ahimamau P.O. Arjunganj Sultanpur Road, Lucknow-226002,Uttar Pradesh
2 Saroj Institute of Technology & Management, Ahimamau P.O. Arjunganj Sultanpur Road, Lucknow-226002,Uttar Pradesh, IN
Source
Asian Journal of Pharmacy and Technology, Vol 3, No 2 (2013), Pagination: 67-72Abstract
Out of the 1114 strains belonging to 29 genera and 105 species of microbes (molds, yeasts and bacteria) isolated from different sources [clinical cases, environment (water, air, soil, droppings of lizards and birds), food and healthy animals], 38.2% were sensitive to lemongrass oil discs containing 50 μg oil/disc. All molds, yeasts, Lactobacillus acidophilus, Morganella morganii, most of the Bacillus spp. Strains (84.3%), aeromonads (78%), Edwardsiella spp. (73.9%), 53.6% pseudomonads, 53.1% streptococci and 50% of Budvicia aquatica and Leminorella ghirmontii strains were sensitive to lemongrass oil (LGO). On the other hand, all Hafnea alvei, Laclercia adecarboxylata, Xenorhabdus luminescens and majority of Salmonella enterica (98.3%), Citrobacter spp. (93.7%), Providencia spp. and Kluyvera cryocrescens (83.3%), Enterobacter spp. (78.2%), Proteus spp. (78%), Escherichia spp. (77.7%), enterococci (73.7%), Serratia spp. (75%) and Erwinia ananas (75%), Pragia fontium (70.6%), staphylococci (69.8%) and Klebsiella spp. (62.7%) strains were resistant to LGO. MIC of LGO for sensitive strains (tested against discs containing 50 μg LGO) varied from 1 μg to 32 μg /ml while none of the resistant strains had MIC <64 μg LGO/ ml. MIC for yeast strains was the least i.e., 1 μg LGO/ ml. LGO had microbicidal activity on E. coli, S. aureus and Candida albicans. LGO instantly killed C. albicans and E. coli, and S. aureus in 10 min at 1 mg/ ml concentration, indicating of its wide spectrum antimicrobial activity at easily achievable concentrations. Study also indicated that LGO is more effective on enterococci in aerobic instead of microaerophilic growth conditions, it is indicative that in-vivo sensitivity results may differ from in-vitro tests.Keywords
Lemongrass Oil, Antimicrobial Activity, Microbes, Microaerophilic GrowthReferences
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- A Review on Marketing of OTC Drugs
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Authors
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1 Saroj Institute of Technology and Management, Ahimamau P.O. Arjunganj Sultanpur Road, Lucknow, IN
1 Saroj Institute of Technology and Management, Ahimamau P.O. Arjunganj Sultanpur Road, Lucknow, IN
Source
Asian Journal of Research in Pharmaceutical Sciences, Vol 3, No 2 (2013), Pagination: 72-78Abstract
Purchase and use of OTC drugs without full knowledge is not only a waste of resources for all stakeholders but can be harmful for consumers. Creating awareness of rational drug use is only possible through continued public education with a broad vision of good health and wellbeing of the society. In developed economies, the four As of marketing has been addressed fairly well but in India, the accessibility and awareness is still on a lower side especially for allopathic OTC drugs .In India, the import, manufacture, distribution and sale of drugs and cosmetics are regulated by the Drugs and Cosmetics Act (DCA) and its subordinate legislation, the Drugs and Cosmetics Rules (DCR).Keywords
Over the Counter (OTC) Drugs, Pharmaceutical Company, Continuous Pharmacist Education (CPE), Corporate Social Opportunity (CSO), Food and Drug Administration (FDA), Corporate Social Responsibility (CSR), Ottom of Pyramid (BOP).References
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- A Natural Cure to Arthritis by Phytomedicines- A Review
Abstract Views :332 |
PDF Views:0
Authors
Affiliations
1 Azad Institute of Pharmacy and Research, Lucknow, Uttar Pradesh, IN
2 Mangalayatan University, Beswan, Aligarh, Uttar Pradesh, IN
3 Saroj Institute of Technology and Management, Uttar Pradesh, IN
1 Azad Institute of Pharmacy and Research, Lucknow, Uttar Pradesh, IN
2 Mangalayatan University, Beswan, Aligarh, Uttar Pradesh, IN
3 Saroj Institute of Technology and Management, Uttar Pradesh, IN
Source
Asian Journal of Research in Pharmaceutical Sciences, Vol 5, No 4 (2015), Pagination: 216-220Abstract
Arthritis is one of the major problems in older age. There are about as many herbal remedies for arthritis as there are arthritis sufferers. Most work by improving the circulation, and encourage fluid elimination. Inflammation due arthritis is mediated through many primary and secondary mediators. Interleukins and TNF-α are one of these mediators. Antiinflammatory agents are used in arthritis widely. A large flora of herbal medicines is available in traditional medicine and basic scientific research has provided an understanding of the efficacy of these remedies in treating arthritis. In recent years, there has been boom in research and industries focusing on herbal remedies to treat a variety of diseases including arthritis. Several developments in clinical studies in carefully designed clinical trials have made the way easier to include herbs as arthritis therapy. This review is focused on the potential role of herbs in treating arthritis and prospects for the future.Keywords
Herbal Remedies, Natural Cure, Arthritis.- A Review-Phytomedicines Used in Treatment of Diabetes
Abstract Views :200 |
PDF Views:1
Authors
Mohd. Yaqub Khan
1,
Irfan Aziz
1,
Bipin Bihari
2,
Hemant Kumar
3,
Maryada Roy
4,
Vikas Kumar Verma
2
Affiliations
1 Azad Institute of Pharmacy and Research, Azadpur, Adjacent CRPF Camp, Bijnour, Lucknow-226002, Uttar Pradesh, IN
2 Saroj Institute of Technology and Management, Ahimamau P.O., Arjunganj Sultanpur Road, Lucknow-226002, Uttar Pradesh, IN
3 Hygia Institute of Pharmacy, Lucknow, Uttar Pradesh, IN
4 Mangalayatan University, Aligarh, Uttar Pradesh, IN
1 Azad Institute of Pharmacy and Research, Azadpur, Adjacent CRPF Camp, Bijnour, Lucknow-226002, Uttar Pradesh, IN
2 Saroj Institute of Technology and Management, Ahimamau P.O., Arjunganj Sultanpur Road, Lucknow-226002, Uttar Pradesh, IN
3 Hygia Institute of Pharmacy, Lucknow, Uttar Pradesh, IN
4 Mangalayatan University, Aligarh, Uttar Pradesh, IN
Source
Asian Journal of Pharmaceutical Research, Vol 4, No 3 (2014), Pagination: 135-154Abstract
Diabetes mellitus (DM), both insulin-dependent DM (IDDM) and non-insulin dependent DM (NIDDM) is a common and serious metabolic disorder throughout the world. Traditional plant treatments have been used throughout the world for the therapy of diabetes mellitus. Among many medications and other alternative medicines, several herbs have been known to cure and control diabetes; additionally they have no side effects. The present paper is an attempt to list of the plants with anti-diabetic and related beneficial effects originating from different parts of world. History showed that medicinal plants have been used in traditional healing around the world for a long time to treat diabetes; this is because such herbal plants have hypoglycemic properties and other beneficial properties, as reported in scientific literature. The medicinal plants, besides having natural therapeutic values against various diseases and considerable works have been done on these plants to treat diabetes mellitus, describes that the antidiabetic activity of medicinal plants is due to the presence of phenolic compounds, avonoids, terpenoids, coumarins and other constituents which show reduction in blood glucose levels. Some of these herbal plants and their active chemical constituents which have a role in the management of diabetes mellitus are compiled here and discussed in this review.Keywords
Diabetes Mellitus, Hypoglycemic Agents, Herbal Medicines, Sulphonylureas, Biguanides.- A Review-Biomedical Engineering-Present and Future Prospective
Abstract Views :292 |
PDF Views:1
Authors
Affiliations
1 Saroj Institute of Technology & Management, Ahimamau P.O. Arjunganj, Sultanpur Road, Lucknow, IN
1 Saroj Institute of Technology & Management, Ahimamau P.O. Arjunganj, Sultanpur Road, Lucknow, IN
Source
Asian Journal of Pharmaceutical Research, Vol 3, No 4 (2013), Pagination: 202-206Abstract
Biomedical engineering is the application of engineering principles and design concepts to medicine and biology for healthcare purposes. This field seeks to close the gap between engineering and medicine: It combines the design and problem solving skills of engineering with medical and biological sciences to advance healthcare treatment, including diagnosis, monitoring, and therapy. Much of the work in biomedical engineering consists of research and development, spanning a broad array of subfields. Prominent biomedical engineering applications include the development of biocompatible prostheses, various diagnostic and therapeutic medical devices ranging from clinical equipment to micro-implants, common imaging equipment such as MRIs and EEGs, regenerative tissue growth, pharmaceutical drugs and therapeutic biological. But more often, sub-disciplines within BME are classified by their association(s) with other more established engineering fields, which can include:
• Biochemical-BME, based on Chemical engineering - often associated with biochemical, cellular, molecular and tissue engineering, biomaterials, and biotransport.
• Bioelectrical-BME, based on Electrical engineering and Computer Science - often associated with bioelectrical and neural engineering, bioinstrumentation, biomedical imaging, and medical devices. This also tends to encompass optics and optical engineering - biomedical optics, bioinformatics, imaging and related medical devices.
• Biomechanical-BME, based on Mechanical engineering - often associated with biomechanics, biotransport, medical devices, and modeling of biological systems, like soft tissue mechanics.
RoHS seeks to limit the dangerous substances in circulation in electronics products, in particular toxins and heavy metals, which are subsequently released into the environment when such devices are recycled. IEC 60601-1-11 (2010) must now be incorporated into the design and verification of a wide range of home use and point of care medical devices along with other applicable standards in the IEC 60601 3rd edition series.